A Short Survey on Genetic Sequences, Chou’s Pseudo Amino Acid Composition and its Combination with Fuzzy Set Theory

D.N. Georgiou1, T.E. Karakasidis2, *, A.C. Megaritis3
1 University of Patras, Department of Mathematics, 265 00 Patras, Greece
2 University of Thessaly, Department of Civil Engineering, 383 34 Volos, Greece
3 Technological Educational Institute of Messolonghi, Department of Accounting, 30200 Messolonghi, Greece

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© 2013 Megaritis et al.

open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

* Address correspondence to this author at the Department of Civil Engineering, University of Thessaly, 38334 Volos, Greece; Tel: +302421074163; Fax: +302421074169; E-mail:


The study of genetic sequences is of great importance in biology and medicine. Sequence analysis and taxonomy are two major fields of application of bioinformatics. In this survey, we present results concerning genetic sequences and Chou's pseudo amino acid composition as well as methodologies developed based on this concept along with elements of fuzzy set theory, and emphasize on fuzzy clustering and its application in analysis of genetic sequences.

Keywords: DNA, Amino acids, genetic sequences, fuzzy clustering, bioinformatics.