GOAPhAR: An Integrative Discovery Tool for Annotation, Pathway Analysis

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RESEARCH ARTICLE

GOAPhAR: An Integrative Discovery Tool for Annotation, Pathway Analysis

Mathur Sachin, 1 Visvanathan Mahesh, * Open Modal , 2 , 3 Svojanovsky Stan2 , 4 , 5 Yoo Byunggil2 , 4 , 5 Srinivas Adagarla B.3 Lushington Gerald H.3 Smith Peter G.2 , 4 , 5
Authors Info & Affiliations
The Open Bioinformatics Journal • 16 Jul 2009 • RESEARCH ARTICLE • DOI: 10.2174/1875036200903010026

Abstract

We have developed the web based tool GOAPhAR (Gene Ontology, Annotations and Pathways for Array Research), that integrates information from disparate sources regarding gene annotations, protein annotations, identifiers associated with probe sets, functional pathways, protein interactions, Gene Ontology, publicly available microarray datasets and tools for statistically validating clusters in microarray data. Genes of interest can be input as Affymetrix probe identifiers, Genbank, or Unigene identifiers for human, mouse or rat genomes. Results are provided in a user friendly interface with hyperlinks to the sources of information.

The tool is freely available at http://bioinformatics.kumc.edu/goaphar/.

Keywords: GOAPhAR, Gene ontology, Annotations and pathways for array research.