e-PROPAINOR: A Web-Server for Fast Prediction of Cα Structure & Likely Functional Sites of a Protein Sequence

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RESEARCH ARTICLE

e-PROPAINOR: A Web-Server for Fast Prediction of Cα Structure & Likely Functional Sites of a Protein Sequence

The Open Bioinformatics Journal 15 Apr 2010 RESEARCH ARTICLE DOI: 10.2174/1875036201004010011

Abstract

e-PROPAINOR (www.math.iitb.ac.in/epropainor/) is a web-server based on extension of PROPAINOR for prediction and computational function elucidation of 3-D structure of proteins. It predicts the Cα structure of a given protein sequence. Computational efficiency and reliability are key features of its software. Moreover, it also gives an estimate of the RMSD of the predicted structure. For the structures predicted with estimated RMSD of the order ≤ 5Å, it predicts likely sites of five major types of protein functions.

Keywords: Protein Structure prediction, Nonparametric regression, Nonparametric Discriminant analysis, Distance geometry.